What are the specific steps for injecting Ocriplasmin?

Ocriplasmin injection is a highly specialized ophthalmic procedure that is only used for one-time intravitreal injection. Its safety and efficacy are highly dependent on standardized procedures. Before use, the drug must be strictly diluted. The recommended dose is 0.125 mg, corresponding to 0.1 mL of diluted solution. The specification of Oak Plasmin Stock Solution is 0.2 mL, and each mL contains 2.5 mg of the drug. Once diluted, sterility must be maintained and used for a single injection only to avoid reuse. During the operation, the patient needs to be in a sterile ophthalmic surgical environment and performed under local anesthesia to reduce discomfort and reduce intraoperative complications.

Under the guidance of a microscope, the doctor punctures the posterior vitreous cavity with a microneedle and slowly injects diluted Oak plasmin into the vitreous cavity of the affected eye. During the injection process, it is necessary to ensure that the medicinal solution is evenly distributed in the traction area to prevent the medicinal solution from overflowing or accidentally entering other eye tissues, thereby ensuring the therapeutic effect. After surgery, patients need to lie still for a few minutes to promote drug diffusion, and undergo short-term follow-up to monitor changes in intraocular pressure and vision. Standardized operations are key to ensuring therapeutic efficacy and can also help reduce common adverse reactions after injection, such as increased intraocular pressure or temporary blurred vision.

Postoperative management is equally important. Patients usually require regular follow-up examinations after injection, including visual acuity examination, OCT imaging evaluation, and intraocular pressure monitoring, in order to detect and deal with potential complications in a timely manner. If intraocular pressure continues to rise, vision decreases significantly, or severe discomfort occurs, you should seek medical treatment immediately. In short, Oak plasmin injection is an important method for non-surgical treatment of vitreomacular traction and macular holes. Its efficacy and safety depend on strict operating specifications and professional postoperative management.

Reference materials:https://www.drugs.com/cdi/ocriplasmin.html