Which hospitals provide obeticholic acid (Obeticholic) treatment?

Obeticholic acid (Obeticholic acid) is a targeted drug for primary biliary cholangitis (PBC). It improves bile acid metabolism and reduces liver inflammation and fibrosis by activating the farnesoid X receptor (FXR). At present, the drug has not been officially approved for marketing in mainland China, so it cannot be routinely prescribed or dispensed in the domestic hospital system. If patients need treatment, they usually need to obtain it through overseas medical institutions or formal drug introduction platforms. Some international medical cooperation hospitals or tertiary hospitals with overseas prescription referral services may provide patients with international prescription consultation to help them obtain overseas drug supply channels within the scope of compliance.

In the international market, obeticholic acid is developed and produced by Intercept Pharmaceuticals. It has been approved in the United States, Europe, Canada, Japan and other countries for the treatment of primary biliary cholangitis, especially for patients who have insufficient response to or cannot tolerate ursodeoxycholic acid (UDCA). The drug is usually supplied in tablet form, in strengths of 5 mg and 10 mg, with each bottle containing 30 tablets. Overseas clinical use data shows that obeticholic acid can significantly reduce alkaline phosphatase (ALP) levels and improve liver inflammation indicators. Therefore, it is widely included in the second-line treatment plan for PBC in European and American countries.

As market demand grows, some countries have begun to produce obeticholic acid generics, such as Mylan Pharmaceuticals in India, Beacon Pharmaceuticals in Bangladesh, and ASEAN Pharmaceuticals in Laos. These generic versions are consistent with the original drugs in terms of ingredients and bioequivalence, but are relatively affordable, making them one of the options for patients to reduce their treatment burden. If domestic patients wish to purchase through overseas pharmacies, they should carefully screen the channels and give priority to products from international pharmaceutical manufacturers that have obtained drug regulatory certification and meet GMP standards.

Reference materials:https://en.wikipedia.org/wiki/Obeticholic_acid