What vitamins and nutrients are needed during capmatinib (Touradida) treatment?

Capmatinib is a highly effective oral targeted drug targeting MET gene mutations or amplifications. It is mainly used to treat patients with advanced or metastatic non-small cell lung cancer (NSCLC). During the treatment process, since drugs may have certain effects on the gastrointestinal tract, liver function and systemic metabolism, reasonable supplementation of vitamins and nutrients can help improve the body's tolerance, reduce adverse reactions, and maintain good physical condition. Patients should supplement scientifically under the guidance of a doctor or nutritionist during the medication period, and should not take large amounts of health products or supplements on their own.

Vitamin B supplementation is very important for patients receiving capmatinib. Capmatinib may cause fatigue, decreased appetite, and mild indigestion, while vitamins B1, B6, and B12 help maintain energy metabolism, promote nervous system health, and help improve appetite and mental state. In addition, some patients may develop anemia or leukopenia due to long-term treatment. Appropriate supplementation of folic acid and vitamin B12 can improve hematopoietic function to a certain extent, but it is necessary to avoid excessive dosage and follow medical advice.

Reasonable supplementation of vitamin D and calcium also deserves attention. Some targeted drugs may have a slight impact on bone metabolism, liver and kidney function, especially long-term treatment, and are prone to vitamin D deficiency or reduced bone density. Vitamin D not only helps with calcium absorption but also has a positive effect on immune regulation. For patients with insufficient dietary intake or lack of sun exposure, vitamin D and calcium preparations can be appropriately supplemented to prevent osteoporosis and bone discomfort.
The intake of high-quality protein and antioxidant nutrients is equally critical. During treatment, patients may experience reduced physical strength and fluctuations in weight. Therefore, it is recommended to have a balanced intake of high-quality protein sources such as lean meat, fish, eggs, and soy products to help maintain muscle mass and immunity. At the same time, moderate intake of fruits and vegetables rich in vitamin C, vitamin E and plant polyphenols can help remove free radicals in the body and reduce oxidative stress caused by drugs. However, care should be taken to avoid supplements that have potential interactions with medications (such as grapefruit, some herbal preparations). Overall, during capmatinib treatment, attention should be paid to a balanced diet, appropriate vitamin and nutrient supplementation, and scientific intervention under the guidance of a doctor, in order to maximize the drug's efficacy and reduce adverse reactions.
Reference: https://www.drugs.com/