How much does a box of macitentan cost? Price comparison of different specifications of packaging and channels

Macitentan (Macitentan) is an oral endothelin receptor antagonist mainly used to treat pulmonary arterial hypertension (PAH). In China, the original drug of macitentan has been approved for marketing and included in medical insurance. The commonly used specification is 10mg*30 tablets, and each box sells for about 4,000 yuan. Since it is included in medical insurance, eligible patients can reduce their actual out-of-pocket costs through medical insurance reimbursement, ensuring its accessibility in the long-term clinical management of patients with pulmonary arterial hypertension.

For domestic patients, the main channel for obtaining macitentan is through certified hospital pharmacies or large chain pharmacies. Since this drug is a prescription drug, patients need to purchase and use it under the guidance of a specialist. At the same time, routine cardiopulmonary function monitoring is required to ensure that the treatment is safe and effective. The supply of medicines in hospital pharmacies is stable, but in some remote areas or newly listed hospitals, medicine stocks may be limited, and patients need to consult in advance or make an appointment to purchase.

In overseas markets, generic drugs of macitentan have also been launched. Taking the same specification of 10mg*30 tablets produced by a Lao pharmaceutical factory as an example, each box sells for about more than 300 yuan, which is far lower than the price of the original drug. This type of generic medicine is basically the same as the original medicine in terms of ingredients, and can provide patients with an alternative with less financial burden. However, when purchasing, patients need to go through formal channels to ensure the quality and legality of the drugs and avoid the risks caused by drugs from informal sources.

Overall, the domestic price of macitentan is about 4,000 yuan per box of the original drug, which can reduce the financial pressure on patients after being included in medical insurance. The price of overseas generic drugs is significantly lower than that of the original drug, but attention must be paid to the formality of the channels. The selection and price differences of different specifications of packaging allow patients to make reasonable choices based on their own condition, medication cycle and economic conditions. During use, following medical advice, regular review and monitoring of adverse reactions are the keys to ensuring efficacy and safety.

Reference materials:https://www.drugs.com/