What are the generic versions of Pemigatinib?

Pemigatinib (Pemigatinib) is a targeted therapy drug mainly used to treat cholangiocarcinoma (CCA) with FGFR2 gene rearrangement. As a new type of targeted drug, pemetinib is widely used in the treatment of patients with advanced cholangiocarcinoma, especially those who are unresponsive to conventional treatments. Due to the higher price of the original drug, generic drugs have become the choice of some patients, especially in developing countries, where generic versions of pemetinib are gradually being promoted on the market.

In overseas markets, generic versions of pemetinib are mainly produced by some pharmaceutical companies. These generic drugs are basically the same as the original drugs in terms of ingredients and efficacy. The more well-known generic versions of pemetinib include multiple pharmaceutical companies from Laos, such as Lao Lucius Pharmaceuticals, Lao ASEAN Pharmaceuticals and Lao Daneng Pharmaceuticals. Take Lucius Pharmaceuticals in Laos as an example. The generic version of pemetinib produced by this company is 4.5mg*14 tablets. The price of each box is significantly lower than that of the original drug, about 700 yuan (the price will change due to exchange rate fluctuations). This price difference makes generic pemetinib the first choice for some patients, especially in some economically disadvantaged areas.

The production of generic pemetinib drugs strictly followsGMP standards and has been certified for quality and efficacy. Generic drugs are basically the same as the brand-name drugs in terms of chemical composition, pharmacological effects, and therapeutic effects. Therefore, patients can usually obtain similar therapeutic effects when using generic drugs as when using the brand-name drugs. At the same time, the production cost of generic drugs is lower, which can reduce the cost of treatment for patients and enable more patients to obtain treatment with the drug.

However, although the therapeutic effects of generic drugs are usually similar to those of brand-name drugs, some patients may have different reactions to generic drugs due to differences in production processes and raw materials. Therefore, when using generic drugs, patients still need to follow the doctor's advice and conduct regular evaluations of efficacy and safety to ensure that the therapeutic effect is not affected. In addition, some patients may need to choose a version of the drug that suits them under the guidance of their doctor.

Reference materials:https://go.drugbank.com/drugs/DB15102