The main functions and pharmacological effects of Trelagliptin tablets

Trelagliptin (Trelagliptin) is a class of oral antidiabetic drugs belonging to dipeptidyl peptidase-4 (DPP-4) inhibitors, used to treat type 2 diabetes . Type 2 diabetes is a common chronic disease characterized by insufficient insulin secretion or insensitivity to insulin action, resulting in abnormally high blood sugar levels. The pharmacological mechanism of trolagliptin is based on its inhibitory effect on DPP-4 enzyme. It has a relatively unique long-term effect and can effectively regulate the blood sugar level of patients and improve the metabolic status of diabetic patients.

The principle of action of trolagliptin is based on the mechanism of a DPP-4 inhibitor. DPP-4 is a naturally occurring enzyme in the human body that can rapidly degrade and inactivate hormones such as glucagon-like peptide-1 (GLP-1). GLP-1 is a hormone that has a degrading effect on blood sugar. It helps regulate blood sugar levels by increasing insulin secretion, inhibiting glucagon secretion, and slowing gastric emptying. DPP-4 inhibitors enhance the biological activity of GLP-1 by extending the half-life of GLP-1, thereby effectively helping diabetic patients control postprandial blood sugar levels.

Similar to otherDPP-4 inhibitors, trolagliptin can achieve hypoglycemic effects by promoting insulin secretion and inhibiting hepatic glucose production. In particular, the drug design of trotagliptin gives it a long-acting effect, allowing patients to take it once a week, thus improving patient medication compliance.

Another important feature of trolagliptin is its long-lasting effect. Compared with other DPP-4 inhibitors, trolagliptin has a longer half-life in the body, which allows patients to take it once a week instead of every day. For patients with type 2 diabetes, long-term drug treatment often requires good compliance, and the long-acting design of trolagliptin helps improve patients' treatment compliance and thereby better control blood sugar levels.

Reference materials:https://en.wikipedia.org/wiki/Trelagliptin