What kind of medicine is Bedaquiline?

Bedaquiline tablets (Bedaquiline) is an anti-tuberculosis drug used to treat multidrug-resistant tuberculosis (MDR-TB). It was developed by Janssen Company of the United States and approved for marketing by the U.S. Food and Drug Administration (FDA).

Bedaquiline tablets belong to a class of anti-tuberculosis drugs with a unique mechanism of action. It mainly inhibits the ATP synthase (ATP synthase) during the cell wall synthesis of Mycobacterium tuberculosis (Mycobacterium tuberculosis), thereby interfering with the energy metabolism of the bacteria and inhibiting its growth and reproduction.

Bedaquiline tablets are mainly used to treat multidrug-resistant tuberculosis, which refers to the situation in which Mycobacterium tuberculosis becomes resistant to conventional Mycobacterium tuberculosis infection treatment drugs (such as isoniazid, rifampin). It is often used as part of a comprehensive treatment regimen for tuberculosis, in combination with other anti-tuberculosis drugs (such as isoniazid, rifampin) to increase the effectiveness of the treatment.

Bedaquiline tablets have been launched in China and have been included in Class B medical insurance. Patients can buy it domestically, but the price is very high. The price of 100mg*24tablets is around 15,000 yuan. For specific prices, please consult the local hospital pharmacy. There are only original drugs abroad, and the more cost-effective ones are Russian original drugs. The price of 100mg*188 tablets is also about 15,000 yuan. The specifications are about 8 times that of domestic ones. Relatively speaking, the price is still very cheap compared to domestic ones. And the ingredients of domestic and foreign original drugs are consistent.