Can Bedaquiline be used for drug-resistant tuberculosis?

Bedaquiline tablets (Bedaquiline) can be used to treat drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB). Drug-resistant tuberculosis refers to a condition in which Mycobacterium tuberculosis becomes resistant to conventional drugs used to treat tuberculosis infections.

Bedaquiline tablets are an anti-tuberculosis drug that works by inhibiting ATP synthase during the cell wall synthesis of Mycobacterium tuberculosis. It is used in combination with other anti-tuberculosis drugs as part of a comprehensive treatment regimen to treat multidrug-resistant tuberculosis. The use of bedaquiline tablets can help improve the success rate of treatment and reduce the recurrence of drug-resistant tuberculosis.

However, the use of bedaquiline tablets should be under the guidance of a physician and in compliance with relevant treatment guidelines and guidelines. Treatment of drug-resistant pulmonary tuberculosis requires an individualized treatment plan that is adjusted based on factors such as the patient's drug resistance, disease severity, and drug resistance pattern. Your doctor will evaluate your patient's specific situation and determine whether bedaquiline is appropriate.

In addition, the use of bedaquiline tablets may be associated with some side effects and safety issues, such as heart problems, liver damage, vision problems, and psychiatric symptoms. Therefore, close monitoring and physician guidance are required before using bedaquiline tablets. Patients should follow their doctor's advice carefully and report any adverse reactions promptly.

Bedaquiline tablets have been launched in China and have been included in Class B medical insurance. Patients can buy it domestically, but the price is very high. The price of 100mg*24tablets is around 15,000 yuan. For specific prices, please consult the local hospital pharmacy. There are only original drugs abroad, and the more cost-effective ones are Russian original drugs. The price of 100mg*188 tablets is also about 15,000 yuan. The specifications are about 8 times that of domestic ones. Relatively speaking, the price is still very cheap compared to domestic ones. And the ingredients of domestic and foreign original drugs are consistent.