How long does Trastuzumab take to treat breast cancer?

Trastuzumab (Trastuzumab) generally requires a certain course of treatment in the treatment of breast cancer. The specific treatment time will vary according to the patient's condition, disease stage and doctor's recommendations. For the treatment of early-stage HER2-positive breast cancer, trastuzumab is usually used in combination with chemotherapy. For example, when used alone or in combination with paclitaxel, the initial dose of trastuzumab for the treatment of metastatic breast cancer is 4 mg/kg, intravenously infused for 90 minutes, followed by 2 mg/kg intravenously for 30 minutes once a week until the disease progresses or becomes intolerable. The standard treatment plan is generally 12 months (1 year).

In the treatment of adjuvant breast cancer it takes approximately 52 weeksIf combined with paclitaxel, docetaxel, or docetaxel/carboplatin, during the first 12 weeks (paclitaxel or docetaxel) or 18 weeks (docetaxel/carboplatin) of chemotherapy, the initial dose is 4 mg/kg intravenously over 90 minutes, followed by 2 mg/kg intravenously over 30 minutes every week. One week after the last weekly dose of trastuzumab, 6 mg/kg of trastuzumab is administered as an intravenous infusion over 30 to 90 minutes every three weeks. If used as a single agent within three weeks of completing a multimodal anthracycline-based chemotherapy regimen, trastuzumab is administered at an initial dose of 8 mg/kg as an intravenous infusion over 90 minutes, followed by doses of 6 mg/kg as an intravenous infusion over 30 to 90 minutes every three weeks. Extending adjuvant therapy beyond one year is not recommended.

Trastuzumab is sold under the brand name Herceptin in China and has entered the scope of Class B medical insurance, but it may be limited to patients who meet the indications for this drug, such as patients with HER2-positive metastatic breast cancer and its adjuvant and neoadjuvant treatment or HER2-positive metastatic gastric cancer. The price is around 6,000 yuan. The original trastuzumab drug has also been launched overseas. The drug ingredients of domestic and foreign original drugs are basically the same. For specific prices and drug details, you can consult the medical consultant. There is currently no generic drug of trastuzumab on the market.