How effective is Sorafenib?

Sorafenib (Sorafenib) is a multi-target kinase inhibitor used to treat some malignant tumors such as renal cell carcinoma (RCC), hepatocellular carcinoma (HCC) and thyroid cancer. Sorafenib has been proven to have certain efficacy in the treatment of hepatocellular carcinoma. Clinical trials have shown that the median survival of patients with hepatocellular carcinoma can be significantly prolonged with sorafenib.

Sorafenib was compared with placebo in the primary clinical study. One study involved 602 patients with hepatocellular carcinoma, one study involved 903 patients with advanced renal cell carcinoma who had failed one of their previous anticancer treatments, and one study involved 417 patients with differentiated thyroid cancer that had developed or spread locally or to other parts of the body and had not responded to radioactive iodine therapy. Sorafenib can slow or stop cancer progression by inhibiting tumor growth and spread. By targeting multiple signaling pathways, it inhibits tumor cell proliferation and angiogenesis. For patients with advanced hepatocellular carcinoma, sorafenib may help relieve symptoms such as pain, fatigue, and loss of appetite. Sorafenib may not produce significant therapeutic effects in all patients. Cancer characteristics and reactions vary from person to person. For some patients, sorafenib may not achieve the desired therapeutic effect.

The original drug of sorafenib has been launched in China and has entered the scope of medical insurance. Different regions have different reimbursement ratios, and the price after reimbursement may vary. SpecificationsThe price of 0.2g*60 tablets may be around 1,200 yuan. The original drug of sorafenib has also been launched overseas, and there are also generic drugs of sorafenib produced in other countries. The price of 0.2g*60 tablets produced by a Bangladesh pharmaceutical factory is around RMB 450 (the price may fluctuate due to the exchange rate). The ingredients of the original drug are basically the same as those of the generic drugs. For specific prices and drug details, please consult the medical consultant of Yaode.