Does Cabozantinib need to be combined with other medications?

Cabozantinib (Cabozantinib) may be used in combination with other drugs to treat certain types of cancer. The purpose of combined therapy is to enhance the therapeutic effect and improve the success rate of cancer treatment through different mechanisms of action. Whether it is necessary to combine treatment with other drugs, and which drugs to use in combination, should be determined based on the patient's specific condition and the doctor's judgment.

The following are some possible combinations with cabozantinib:

1.Combination chemotherapy: In some cases, cabozantinib can be used with chemotherapy drugs, especially when treating advanced or metastatic cancer. Chemotherapy drugs can destroy cancer cells in different ways, and combining them with cabozantinib may enhance the effectiveness of the treatment and slow the progression of the disease.

2.Combined radiation therapy: For some locally advanced cancers, cabozantinib may be used in combination with radiation therapy. Radiation therapy can be used to locally control tumors and inhibit the growth of cancer cells by damaging their DNAstructure. Use in combination with cabozantinib may help enhance the effectiveness of radiation therapy and reduce tumor growth.

3.Combination immunotherapy: In some cases, cabozantinib may be used in combination with immunotherapy drugs, especially to treat renal cell carcinoma. Immunotherapy activates the patient's own immune system to attack and destroy cancer cells. Use in combination with cabozantinib may help enhance the effectiveness of immunotherapy and improve treatment response rates.

Cabozantinib is not currently on the market in China and is therefore not included in medical insurance because it requires approval from the National Medical Products Administration. Therefore, patients cannot purchase it domestically and need to purchase it through overseas channels. There are original and generic cabozantinib drugs abroad. The original drugs are mainly Japanese original drugs, Turkish original drugs and European original drugs. The price is relatively high, ranging from 35,000 to 46,000 yuan. Foreign generic drugs are mainly Lao generic drugs and Bangladeshi generic drugs, with prices ranging from 1,300 to 2,700 yuan. The price is much cheaper than original drugs and is more suitable for the needs of patients in ordinary families. The ingredients of original drugs and generic drugs are basically the same.

It should be emphasized that the combination treatment plan should be formulated by professional doctors based on the patient's specific condition and pathological type. Different cancer types and individual patient differences may lead to different treatment strategies. Therefore, when considering whether to use other drugs in combination for treatment, you should consult your doctor and follow your doctor's prescriptions and recommendations for treatment. Combination therapy may also bring additional adverse reactions and risks. Doctors will monitor and adjust based on the patient's overall condition and treatment response to ensure the safety and effectiveness of the treatment.