Long-term side effects of Cabotegravir

Cabotegravir (Cabotegravir) is a new type of antiretroviral drug. Although its short-term side effects are relatively mild, long-term use may cause some side effects. Long-term side effects are adverse reactions or health problems that patients may experience after using a drug for a longer period of time. It is important to emphasize that each patient's response may be different and the severity of side effects varies among individuals. Here are some possible long-term side effects of cabotegravir:

Liver problems: Long-term use of cabotegravir may cause liver problems, including elevated liver enzymes and abnormal liver function. During treatment, doctors usually test liver function regularly to ensure that the effects of the drug on the liver are within acceptable limits.

Kidney problems: Some patients may develop kidney problems after long-term use of cabotegravir, including reduced glomerular filtration rate and kidney damage. Likewise, doctors will monitor a patient's kidney function to make sure the drug's effects on the kidneys don't cause serious problems.

Decreased bone density: Long-term use of antiretroviral drugs, including cabotegravir, may cause a decrease in bone density and increase the risk of fractures. Particularly for patients on long-term use, especially elderly patients, measures such as bone density monitoring and dietary modification may be necessary.

Pancreatitis: There are reports that the use of cabotegravir may be associated with an increased incidence of pancreatitis. Pancreatitis is an inflammation of the pancreatic tissue that may require hospitalization in severe cases.

Cardiovascular problems: Some studies suggest that use of cabotegravir may be associated with cardiovascular problems, such as an increased rate of heart events. Cardiovascular problems may be related to the drug's long-term effects and effects on blood lipids and blood sugar, but the exact mechanism is unknown.

Abnormal lipid metabolism: Long-term use of antiretroviral drugs may affect lipid metabolism, leading to increased cholesterol and triacylglycerol levels. High blood lipids may increase the risk of cardiovascular disease.

Immune system problems: Long-term use of antiretroviral drugs may have an impact on the immune system, leading to changes in immune function. This may increase the patient's risk of contracting other diseases.

It should be emphasized that the above-mentioned side effects may occur in some patients, but not all patients. Many patients can safely use cabotegravir long-term without serious side effects. Doctors will take the patient's individual situation into consideration when carrying out treatment, and conduct regular monitoring and evaluation to deal with possible side effects in a timely manner.

When using cabotegravir for a long time, patients should follow the doctor's advice and treatment plan, and have regular follow-up and examinations. If you notice any discomfort or side effects, you should report it to your doctor in time. Doctors will evaluate the patient's symptoms and signs and may take appropriate measures to alleviate side effects or adjust treatment.

Cabotegravir is not currently on the market in China, so patients cannot purchase it domestically and need to purchase cabotegravir through overseas channels. Foreign cabotegravir only has original drugs, mainly European original drugs, and the price is very high, about 16,000 yuan.

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