How effective is the Indian version of sofosbuvir and velpatasvir (Epclusa)?

The Indian version of sofosbuvir velpatasvir (Epclusa) combination is a generic drug. Its pharmaceutical ingredients are basically the same as those of the original drug of sofosbuvir velpatasvir combination, but the manufacturers are different and the prices are also different. The specifications (400mg+100mg)*28 tablets produced by NATCO Pharmaceutical Factory in India are priced at around 1,580 RMB per box. Mylan Pharmaceutical Factory in India The price of the production specification (400mg+100mg) * 28 tablets per box is around RMB 1,150 (the price may fluctuate due to exchange rate effects). Patients need to purchase generic drugs through formal channels.

Sofosbuvir and velpatasvir are a combination of sofosbuvir and velpatasvir, used to treat chronic hepatitis C - a disease caused by a viral infection of the liver. Sofosbuvir and velpatasvir combinationcan be used in combination with another antiviral drug(ribavirin). These drugs help the immune system fight the virus by reducing the load of hepatitis C virus in the body and may help the liver recover. Untreated chronic hepatitis C infection can lead to serious problems such as cirrhosis or liver cancer. Epclusa可以帮助丙肝患者，但它可以使乙肝恶化。

The original drug of sofosbuvir and velpatasvir has been launched in China and has entered the scope of Class B medical insurance. The domestic trade name is protonsa, and the specification (400mg+100mg)*28 tablets is priced at about 4,000 yuan per box. The original drug of sofosbuvir and velpatasvir has also been launched overseas. There are also generic drugs of sofosbuvir and velpatasvir produced in other countries. The price of the specification (400mg + 100mg) * 28 tablets produced by Everest Pharmaceutical Factory in Bangladesh is about 850 yuan per box (the price may fluctuate due to the exchange rate). The generic drugs produced abroad are basically the same as the original drugs at home and abroad.