Is Capmatinib available in China?

Capmatinib (Capmatinib) belongs to the tyrosine kinase inhibitor (TKI) category. It was developed by Novartis Pharmaceuticals (Novartis Pharmaceuticals) and is used to treat patients with non-small cell lung cancer (NSCLC) carrying METexon14 skipping mutations.

METexon14 skipping mutations are rare but clinically important genetic mutations that lead to abnormal activation of the MET receptor kinase. This abnormal activation can promote the growth and spread of cancer cells, leading to the progression of NSCLC. The mechanism of action of capmatinib is to slow down or inhibit the proliferation and spread of cancer cells by inhibiting the activity of MET kinase and interfering with the conduction of abnormal signaling pathways.

Clinical trial results show that capmatinib has a certain degree of therapeutic effect on patients with NSCLC carrying METexon14 skipping mutations, and has been approved by the corresponding regulatory agencies for the treatment of this specific subgroup of patients.

Some side effects may occur during the use of capmatinib, including but not limited to fatigue, nausea, vomiting, diarrhea, rash, etc. Therefore, before using capmatinib, doctors will evaluate a patient's overall health and weigh the risks and benefits of treatment on an individual basis.

As a prescription drug, capmatinib needs to be used under a doctor's supervision and in accordance with the doctor's medication recommendations and dosage instructions. If patients experience any discomfort or adverse reactions during use, they should report it to their doctor immediately.

Capmatinib is not currently on the market in China, so patients cannot purchase it domestically. Overseas capmatinib is divided into original drugs and generic drugs. The original drug is mainly Novartis original drug. The price is around 35,000 yuan and the specification is 200mg*60The price of generic drugs is very cheap, mainly Laos generic drugs, which cost about three to four thousand yuan. The ingredients of original drugs and generic drugs are basically the same.