Where to buy sirolimus

Sirolimus (sirolimus) has potent immunosuppressive properties associated with inhibition of the mammalian target of rapamycin (mTOR). Sirolimus, together with cyclosporine and steroids, reduces the incidence of acute rejection in kidney transplant recipients and is approved by the U.S. Food and Drug Administration (FDA) for use in kidney transplantation. The inherent nephrotoxicity makes sirolimus an attractive alternative to calcineurin inhibitors (CNIs), which has led to its off-label use in combination with other drugs in liver transplantation.

Sirolimus has strong anti-angiogenic effects that inhibit tumor growth in experimental models. From a clinical perspective, kidney transplant studies have shown that sirolimus reduces the incidence of skin cancer and other malignancies. Recent liver transplant studies have reported improved survival rates in patients with HCC treated with sirolimus and is also suitable for the treatment of patients with lymphangioleiomyomatosis (LAM).

SirolimusThe original drug has been launched in China and has entered the scope of Class B medical insurance. SpecificationsThe price of each box of 1mg*10 tablets is about 400 yuan. Domestic drugs are only available for patients with anti-rejection reactions in organ transplantation. Patients who do not meet the conditions may not be able to purchase this drug. Domestic hospitals or pharmacies may resell this drug. The original sirolimus drug has also been launched overseas. The price of the Turkish version of Specifications1mg*100 tablets per box is around RMB 2,000 (the price may fluctuate due to exchange rates). The ingredients of the original drugs marketed in China are basically the same as those of foreign original drugs. Currently, there are no generic sirolimus drugs produced in other countries.