Capmatinib side effects

Capmatinib (Capmatinib) is a targeted therapy drug for specific types of cancer. Although it mainly targets tumor cells, like all drugs, it may also cause some side effects. The severity and incidence of side effects vary on an individual basis, and different patients may respond differently. Here is a detailed explanation of some of the common and serious side effects that can occur with capmatinib.

Common side effects:

1.Nausea and vomiting: This is one of the common side effects of capmatinib. Patients may feel nauseous or experience vomiting. These symptoms can often be managed by working with your doctor, such as by adjusting your medication schedule or using anti-nausea medications.

2.Diarrhea: Some patients may experience diarrhea, which may be due to the effect of the drug on the intestines. Staying well hydrated and getting fiber in your diet can help reduce diarrhea symptoms.

3.Skin rash and skin reactions: Some patients may experience skin reactions such as rash, itching, and dry skin. These reactions may require special skin care and communication with your doctor if necessary.

4.Fatigue and weakness: Some patients may experience fatigue and weakness. This may affect daily activities and quality of life. Patients need to rest and, when possible, moderate exercise to help relieve fatigue symptoms.

5.Loss of appetite: Capmatinib may cause loss of appetite, thus affecting the patient's diet. Maintaining a balanced diet and eating moderate amounts may help alleviate this problem.

Serious Side Effects: Although most patients experience mild adverse reactions while taking capmatinib, serious side effects can sometimes occur. Here are some examples of serious side effects:

1. Abnormal liver function: Capmatinib may affect the liver, leading to abnormal liver function. This may manifest as symptoms such as jaundice and elevated liver enzymes. Patients need to check their liver function regularly during medication and communicate with their doctor in a timely manner.

2.Hematological abnormalities: Hematological abnormalities such as anemia, leukopenia, and thrombocytopenia may sometimes occur when using capmatinib. This may increase the risk of infection and bleeding. Patients need to have regular blood tests while taking the medication.

3.Respiratory problems: A small number of patients may have difficulty breathing or other respiratory problems. If you develop shortness of breath, wheezing, or other breathing problems, seek medical attention immediately.

4.Eye problems: Capmatinib may cause eye problems, including eye pain, blurred vision, etc. Patients should have regular eye examinations and contact their doctor promptly.

5.Skin reactions: Although rash is a common side effect, serious skin reactions such as toxic epidermal necrolysis (TEN) or drug-associated skin necrosis (SCAR) may occur in some patients. These are serious drug allergic reactions that require immediate discontinuation of the drug and emergency treatment.

6.Severe allergic reactions occur: Individual patients may be allergic to capmatinib, manifesting as severe allergic reactions, such as urticaria, shortness of breath, throat swelling, etc. If an allergic reaction occurs, stop taking the medication immediately and seek medical attention.

Please note that the above list of side effects is not exhaustive and does not mean that all patients will experience these reactions. During the use of capmatinib, if the patient has any unusual symptoms or reactions, he should communicate with his doctor in time for timely treatment and adjustment of the treatment plan. Doctors will evaluate the severity of side effects based on the patient's specific situation and take appropriate measures as necessary to ensure the safe and effective use of the drug.

Capmatinib is not currently on the market in China, so patients cannot purchase it domestically. Capmatinib abroad is divided into original drugs and generic drugs. The original drug is mainly the original drug from Novartis, with a price of about 35,000 yuan and a specification of 200mg*60; the price of generic drugs is very cheap, mainly Laos generic drugs, with a price of about 3,000 to 4,000 yuan. The ingredients of original drugs and generic drugs are basically the same.