Which generation of targeted drug is Ceritinib/Ceritinib?

Ceritinib/Ceritinib (Ceritinib) is a second-generation targeted drug. Targeted drugs are a class of drugs that target specific molecules or signaling pathways to inhibit or block the growth and spread of cancer cells while minimizing damage to normal cells. The development of these drugs is based on a deep understanding of cancer biology, especially the abnormal signaling pathways and molecular changes within cancer cells.

The first generation of targeted drugs mainly targets some specific receptors or proteins on the surface of tumor cells, such as EGFR (epidermal growth factor receptor) inhibitors, which are used to treat EGFR mutation-positive lung cancer. However, because cells may become resistant or develop new mutated forms, scientists continue to work to find drugs that are more selective and have longer-lasting effects.

Second-generation targeted drugs, such asceritinib/ceritinib, target more complex signaling pathways in cancer cells and are generally more selective than first-generation targeted drugs and can inhibit more different molecular targets. Ceritinib/Ceritinib targets the activity of ALK (tyrosine kinase) fusion protein and is used to treat patients with ALK fusion-positive non-small cell lung cancer.

Since then, with the advancement of science, third-generation targeted drugs and more innovative drugs have been continuously developed to better understand the biological characteristics of cancer cells and target different cancer subtypes. Targeted therapy is an important direction in the field of cancer treatment, providing patients with more targeted and personalized treatment strategies.

Ceritinib/Ceritinib has been launched in China and has been included in medical insurance. Patients can purchase it domestically, but the price is high. Please consult your local pharmacy for details. Foreign original drugs are divided into original drugs and generic drugs. Foreign original drugs are mainly Swiss Novartis original drugs. Specification150mg*150The price is about13,500 yuan. Generic drugs mainly include Bangladeshi version, with specifications of 150mg*30 and the price is around 1,300 yuan. The ingredients of original drugs and generic drugs are basically the same.