What are the adverse reactions of Ceritinib?

Ceritinib/Ceritinib (Ceritinib) is a targeted therapy drug mainly used to treat ALK (tyrosine kinase) fusion-positive non-small cell lung cancer (NSCLC) patients. Although Ceritinib is an effective treatment option for many patients, like any drug, it may cause some adverse effects. In this article, we will discuss in detail the possible adverse reactions of ceritinib/ceritinib, including common and serious reactions, and describe how to manage and mitigate these reactions.

1. Common adverse reactions

1.Nausea and vomiting: Nausea and vomiting are one of the most common adverse reactions when using ceritinib/ceritinib. These reactions usually occur early in treatment and may lessen over time. Doctors may advise patients to avoid eating large amounts of food before and after taking medication to reduce nausea. Also, some medications may be necessary to control nausea and vomiting.

2.Diarrhea: Diarrhea is another common adverse reaction. Like nausea and vomiting, diarrhea usually occurs early in treatment but may lessen as treatment progresses. Patients can try to avoid high-fat, high-fiber foods, increase fluid intake, and avoid overuse or abuse of antidiarrheal medications.

3.Fatigue: Patients taking ceritinib/ceritinib may experience fatigue and weakness. This may affect daily living and mobility. When feeling tired, patients should try to rest as much as possible, exercise moderately, maintain a healthy lifestyle, and follow the doctor's recommendations.

4.Discomfort and loss of appetite: Some patients may experience discomfort and loss of appetite during treatment. This can lead to weight loss and malnutrition. It is important to maintain a healthy diet, consume adequate nutrients, and discuss possible complementary nutritional support with your medical team.

5.Nasal congestion and runny nose: Nasal congestion and runny nose are also usedCeritinib/CeritinibA relatively common adverse reaction. Keeping your nasal passages moist and avoiding excessive nose blowing can help reduce these symptoms.

6.Abnormal liver function:Ceritinib/Ceritinib may have effects on liver function, including increased liver enzymes. Therefore, doctors typically monitor patients' liver function during treatment to ensure safety and handle any abnormalities promptly.

2. Serious adverse reactions: Although most patients will experience mild adverse reactions when using ceritinib/ceritinib, some patients may experience more serious adverse reactions, which may require emergency treatment and treatment. The following are some possible serious adverse reactions:

1.Lung problems:Ceritinib/Ceritinib Lung problems, including pneumonia, pulmonary fibrosis, and difficulty breathing, may occur during use. If patients develop shortness of breath, cough, chest pain, or other respiratory problems during treatment, they should seek medical attention immediately.

2.Arrhythmias:Ceritinib/Ceritinib may cause arrhythmias, including QT interval prolongation. This can cause heart rhythm disturbances and even be life-threatening. Patients should receive regular EKG monitoring during treatment to ensure heart health.

3.Hyperglycemia:Ceritinib/CeritinibDuring use, some patients may develop hyperglycemia and even develop diabetes. It is important to monitor blood sugar levels and follow your doctor's recommendations for managing blood sugar.

4.High cholesterol:Ceritinib/Ceritinib may cause elevated cholesterol levels, which may increase cardiovascular risk. Patients should check their cholesterol levels regularly and take appropriate steps to manage high cholesterol.

5.Vision problems:Ceritinib/Ceritinib may cause vision problems, including blurred vision, dry eyes, and other eye conditions. If patients develop vision problems during treatment, they should seek medical attention promptly.

The adverse reactions listed above are not exhaustive, and other adverse reactions may occur when using ceritinib/ceritinib. Therefore, patients should pay close attention to their physical condition during treatment and report any new symptoms and feelings to the medical team at any time. Timely communication with your doctor can help detect and deal with potential problems in advance, ensuring the safety and effectiveness of treatment.

Ceritinib/Ceritinib has been launched in China and has been included in medical insurance. Patients can purchase it domestically, but the price is high. Please consult your local pharmacy for details. Foreign original drugs are divided into original drugs and generic drugs. Foreign original drugs are mainly Swiss Novartis original drugs. Specification150mg*150The price is about13,500 yuan. Generic drugs mainly include Bangladeshi version, with specifications of 150mg*30 and the price is around 1,300 yuan. The ingredients of original drugs and generic drugs are basically the same.