Dolutegravir Sodium Warnings and Precautions

Dolutegravir Sodium (Dolutegravir Sodium) is an antiretroviral drug used to treat human immunodeficiency virus (HIV) infection and has significant efficacy. However, there are some warnings and precautions that patients and doctors need to pay special attention to when using dolutegravir sodium to ensure the safety and effectiveness of the drug. The following is a detailed introduction to the warnings and precautions for dolutegravir sodium:

1.Drug allergic reactions: During the use of dolutegravir sodium, some patients may experience drug allergic reactions, including rash, urticaria, edema, shortness of breath and other symptoms. If a severe allergic reaction occurs, patients should stop using the drug immediately and seek medical advice. The doctor will handle and adjust the treatment plan according to the specific situation.

2. Abnormal liver function: Patients taking dolutegravir sodium may experience abnormal liver function, including elevated liver enzymes. During treatment, doctors usually monitor liver function regularly to make sure the medicine is not causing damage to the liver. If significant liver function abnormalities occur, drug dosage adjustments may need to be made or alternative treatment options may need to be considered.

3. Nervous system problems: A small number of patients may develop neurological problems, such as headache, dizziness, insomnia, etc. when using dolutegravir sodium. If these symptoms seriously affect the quality of life, the patient should inform the doctor in time so that appropriate treatment can be carried out.

4.Pancreatitis: In rare cases, the use of dolutegravir sodium may be associated with the development of pancreatitis. If the patient develops abdominal pain, nausea, vomiting and other symptoms, he should seek medical treatment immediately, and the doctor will conduct corresponding examination and treatment.

5. Renal function: Dolutegravir sodium may affect renal function and lead to abnormal renal function. Doctors usually monitor kidney function regularly while using the drug to make sure the drug is not causing damage to the kidneys. If renal function abnormalities occur, medication dosage adjustments or other measures may need to be taken.

6.Drug interactions: Dolutegravir sodium may interact with other drugs, affecting their absorption, metabolism or excretion. While taking dolutegravir sodium, patients should inform their doctor about all medications they are taking, including prescription drugs, over-the-counter drugs, herbal supplements, etc. Doctors can assess the risk of drug interactions and make adjustments accordingly.

7.Children and Pregnant Women: Special caution and caution are required when using dolutegravir sodium in children, pregnant women, and lactating women. When using drugs in these special populations, doctors will develop an appropriate medication regimen based on the patient's condition and evaluate potential risks and benefits.

8.Avoid missing doses: To ensure the efficacy of the drug, patients should not miss doses of dolutegravir sodium. If you accidentally miss a dose, take it as soon as you notice and continue as normal at the next dose time.

9.Medical monitoring: During the use of dolutegravir sodium, patients should receive regular medical monitoring, including examinations of liver function, renal function, viral load and immune function. This helps doctors understand the efficacy of the drug and the patient's health status and adjust the treatment plan in a timely manner.

In summary, the warnings and precautions for dolutegravir sodium are critical to ensuring the safety and effectiveness of the drug. Before using drugs, patients should consult a professional doctor to fully understand the risks and benefits of the drug, use the drug correctly according to the doctor's guidance and prescription, and receive regular medical monitoring to achieve the best therapeutic effect. If you have any discomfort or concerns, you should seek help and advice from your doctor promptly.

Dolutegravir sodium has been launched in China, but it has not yet been included in medical insurance. Patients can purchase it in hospital pharmacies at a price of around 1,200 yuan. Please consult the local hospital pharmacy for specific prices. Dolutegravir sodium is cheaper abroad, mainly Indian generic drugs, with a price of around 350 yuan, and the ingredients of domestic original drugs and foreign generic drugs are basically the same.