Can Everolimus treat breast cancer?

Everolimus (Everolimus) may be used to treat breast cancer in certain circumstances, specifically a specific type of breast cancer called endocrine receptor-positive, human epidermal growth factor receptor2negative (ER+/HER2-) advanced breast cancer.

Breast cancer is a common female malignancy with multiple subtypes. Among them, endocrine receptor positivity in breast cancer means that the tumor cell surface has estrogen or progesterone receptors, which increases the tumor's dependence on hormones. The application of everolimus in the treatment of this type of breast cancer is mainly for patients with relapsed or refractory disease, especially patients who are resistant to endocrine therapy.

Everolimus is used to treat breast cancer in combination with endocrine therapy (such as estrogen receptor modulators), which helps block growth signaling pathways within cells, thereby inhibiting tumor growth. This is achieved through its inhibitory effect on the TOR (targeting of rapamycinase) signaling pathway. The introduction of everolimus can slow the growth and spread of tumors, thereby extending patient survival in some cases.

However, everolimus is not a standard treatment for all breast cancer patients, and its use usually needs to be closely monitored by a doctor to ensure that patients get the best treatment results. In addition, everolimus may cause some side effects, including oral ulcers, infections, gastrointestinal discomfort, etc. Therefore, patients should pay close attention to their physical condition during use and communicate with their doctors in a timely manner.

Everolimus has been approved for marketing in my country, and has been included in the national medical insurance. The price is about 4000~5000 yuan. It takes about 2 boxes of everolimus per month. For specific prices and medical insurance reimbursement policies, please consult the local hospital pharmacy or medical insurance bureau. The cheaper ones abroad are mainly Indian generic drugs, the price is around 700~1,500yuan, and the ingredients of the drugs are basically the same as those in China.