How many years should you take Regorafenib?

Regorafenib(Regorafenib) has no upper limit. According to its prescription information, the recommended dosage is 160mg, every The tablets may be taken orally once daily for the first 21 days of a 28-day cycle. The entire tablet may be swallowed with water after a low-fat meal containing less than 600 calories and less than 30% fat. Treatment is continued until disease progression or unacceptable toxicity occurs.

The length of treatment cycles can vary based on individual differences. Some patients may achieve optimal results within several months, while others may take longer. Once a patient reaches the maximum tolerated dose of regorafenib and maintains stable disease status, physicians may consider continuing the drug. The highest dose in clinical studies was 220 mg per day. The most commonly observed adverse drug reactions at this dose were dermatological events, dysphonia, diarrhea, mucosal inflammation, dry mouth, decreased appetite, hypertension, and fatigue.

RegofenibThe original drug has been launched in China and has entered the scope of Class B medical insurance. Reimbursement is limited to patients who meet the indications. SpecificationThe price of each box of 40mg*28 tablets is around RMB 5,000. The reimbursement ratio is different in different regions, and the price after reimbursement is different. The Turkish version of regorafeniboriginal drug specifications 40mg*28 tablets sold overseas is priced around RMB 6,400 per box (the price may fluctuate due to exchange rates). There are also generic regorafenib drugs produced in other countries, and their drug ingredients are basically the same as those of the original drug. The price of a box of 40mg*90 tablets produced by a Bangladesh pharmaceutical factory is around 2,900 yuan (the price may fluctuate due to exchange rates).