Is Everolimus effective in treating breast cancer?

Everolimus (Everolimus), as a targeted therapy drug, has been studied and applied in some breast cancer patients. It is often used along with other drugs to treat certain types of breast cancer. However, its efficacy varies depending on the patient's specific condition and the subtype of breast cancer. Here is some information about everolimus in the treatment of breast cancer:

1.Indications: Everolimus is commonly used to treat hormone receptor-positive (ER+) and HER2-negative advanced or metastatic breast cancer. This subtype of breast cancer may become resistant to hormonal therapy, and everolimus may be used as a treatment option.

2.Combination medication: Everolimus is often used in combination with hormonal treatments (such as anatropide or isdorol). This combination therapy can inhibit the proliferation and survival of cancer cells by inhibiting the mTOR signaling pathway to improve the therapeutic effect.

3.Clinical trial data: In some clinical trials, everolimus combined with hormonal therapy has shown certain efficacy in patients with advanced breast cancer. For example, in the BOLERO-2 study, patients treated with everolimus plus isodorol had significantly longer progression survival. However, efficacy varies depending on the patient's disease characteristics and other factors.

4.Side effects and tolerance: Everolimus may be accompanied by some side effects, such as oral ulcers, rash, fatigue, nausea, diarrhea, etc. Patients may need to work closely with their doctor during use to monitor side effects and take appropriate steps to reduce discomfort.

Overall, everolimus shows some efficacy in treating patients with certain types of breast cancer, but its effectiveness varies among individuals. When considering everolimus for breast cancer treatment, patients should have a detailed discussion with their doctor to understand possible treatment effects, side effects, and individualized treatment options. Treatment decisions should be based on the patient's condition, medical history, and physician recommendations. If you or someone you know is considering everolimus for breast cancer, it is important to consult a medical professional for accurate and personalized guidance.

Everolimus has been approved for marketing in my country, and everolimus has been included in the national medical insurance, and the price is about 4000~5000RMB is around 2 boxes of everolimus per month. For specific prices and medical insurance reimbursement policies, please consult the local hospital pharmacy or medical insurance bureau. The cheaper ones abroad are mainly Indian generic drugs, the price is around 700~1,500yuan, and the ingredients of the drugs are basically the same as those in China.