What is the difference between overseas Venetoclax and domestic Venetoclax?

The difference between Venetoclax produced and marketed overseas and Venetoclax marketed domestically may lie in different prices, different manufacturers, and different production specifications. Overseas, venetoclax is available as both original and generic drugs. Domestic venetoclax is sold under the name of venetoclax, and there are imported versions of the original version. The ingredients of domestic and foreign original drugs and overseas generic drugs are basically the same, and can be used to treat chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL).

The original drug venetoclax was developed by AbbVie Biopharmaceuticals. It is the first BCL-2 inhibitor approved by the U.S. Food and Drug Administration (FDA) and can be combined with other drugs. Used together, it is often used to treat acute myeloid leukemia in adults 75 years of age or older, or in adults who are unable to use standard chemotherapy due to other medical conditions. It can induce the rapid and efficient onset of apoptosis in CLL cells, which may take effect within 24 hours and cause tumor lysis syndrome.

The domestically marketed Venetoclax can currently be found in the Class B medical insurance catalog, but it is only available for medical insurance reimbursement for adult patients with acute myeloid leukemia. Patients who do not meet the conditions need to purchase it at their own expense. SpecificationsThe price of 100mg*142 tablets per box is around 3,000 RMB. The reimbursement ratio is different in different regions, and the price after reimbursement may be different. The Turkish version of venetoclax original drug listed overseas, specifications100mg*112 tablets, is priced around RMB 16,500 per box (the price may vary due to the exchange rate) Fluctuations), the generic drug of venetoclax produced by Bangladesh Yaopin International, with a specification of 100mg*120 tablets, is priced at around 4,700 yuan per box (the price may fluctuate due to the exchange rate). For specific prices and drug details, please consult Yaode’s medical consultant.