Treatment of resistance to romiplostim

Romiplostim (Romiplostim) is an important TPO-RA that offers an advanced treatment option for patients with thrombocytopenia and works by increasing platelet production and thereby increasing platelet counts. Increased platelet counts may reduce the need for platelet transfusions and reduce bleeding events in a variety of conditions. Romiplostimbinds to and activates TPO-R on megakaryocyte precursors, activating a variety of cell signaling pathways, leading to enhanced cell growth and cell viability, thereby increasing platelet production.

Although there are extensive data on the use of romiplostim in adult and pediatric patients with chronic ITP, data on the evolution of romiplostim in newly diagnosed ITP patients suggest that it may be useful in the early treatment of adults unresponsive to corticosteroids. Additionally in these patients with early-stage disease, there is the possibility of prolonged or no response to treatment. However, everyone’s physique is different and their resistance to drugs is also different. If you feel unwell, please inform your doctor in time.

RomiplostimThe original drug has been approved by the State Food and Drug Administration for marketing. Due to its short time on the market, it is not included in the scope of medical insurance. It may be difficult to purchase it domestically. The price of the original version in Hong Kong may be RMB 10,000 per pill (the price may fluctuate due to exchange rates). The price of the European version of romiplostim the original drug may be 11,000 RMB per pill, the German version may be 9,850 RMB per pill, and the Hong Kong version may be 8,900 RMB per pill (the price may fluctuate due to the exchange rate). The ingredients of the drugs are basically the same. For specific prices and drug details, please consult Yaode’s medical consultant.