The Difference Between Eltrombopag and Romiplostim

Romiplostim and Eltrombopag are both medicines used to treat certain types of thrombocytopenia. Romigrastim is a platelet growth factor that promotes the increase of platelets by activating the process of platelet production. Eltrombopag is a platelet production agonist that stimulates stem cells in the bone marrow to increase the number of platelets produced by binding to platelet production receptors.

Romigrastim needs to be administered by subcutaneous injection. It is suitable for idiopathic/immune thrombocytopenia and chronic immune thrombocytopenia. It is usually injected subcutaneously once a week, and the dose is also adjusted according to the patient's platelet count. Eltrombopag can be administered orally and is mainly used to treat immune-mediated idiopathic thrombocytopenia and chronic hepatitis B-related thrombocytopenia. It is usually taken orally once daily, and the dose is adjusted according to the patient's platelet count. Both drugs may cause adverse reactions such as headache, nausea, diarrhea, and fatigue. However, specific adverse effects and severity may vary among individuals.

RomiplostimThe original drug has been approved by the State Food and Drug Administration for marketing. Due to its short time on the market, it is not included in the scope of medical insurance. It may be difficult to purchase it domestically. The price of the original version in Hong Kong may be RMB 10,000 per pill (the price may fluctuate due to exchange rates). The price of the European version of romiplostim the original drug may be 11,000 RMB per pill, the German version may be 9,850 RMB per pill, and the Hong Kong version may be 8,900 RMB per pill (the price may fluctuate due to the exchange rate). The ingredients of the drugs are basically the same. For specific prices and drug details, please consult Yaode’s medical consultant.