How to take Ruxolitinib

Ruxolitinib tablets are oral preparations, and common strengths include 5mg, 10mg, 15mg, 20mg and 25mg. When used to treat patients with myelofibrosis, the recommended dose of ruxolitinib tablets depends on the patient's baseline platelet count. For example, patients with platelet counts between 50-100x10^9/L can take up to 5 mg twice a day, and patients with platelet counts above 100x10^9/L can take up to 15 mg twice a day.

The recommended dose for patients with polycythemia vera should be 10 mg twice daily.The dose for non-responders may be increased to 25 mg twice daily if hemoglobin, neutrophil count, and platelets are normal. The recommended dose for acute graft-versus-host disease is 5-10 mg orally twice daily, starting with 5 mg twice daily for 3 days and then increasing to 10 mg twice daily. The recommended dose for chronic graft-versus-host disease is 10 mg twice daily; dose adjustment may be required in patients with prior treatment failure based on bilirubin, ANC, or platelet response.

Ruxolitinib tabletsThe original drug has been launched in China and is included in the scope of Class B medical insurance. It is limited to patients who meet the indications. Specification The price of each box of 5mg*60 tablets may be around RMB 3,000. The Turkish version of ruxolitinib tablets listed overseas, Specifications20mg*56 tablets, may be priced around RMB 8,000 per box (the price may fluctuate due to exchange rates). There are also ruxolitinib tablets produced in other countries. For example, the price of 5mg*50 tablets produced by Bangladesh Yaopin International may be around 1,400 yuan per box (the price may fluctuate due to exchange rates). Its pharmaceutical ingredients are basically the same as those of domestic and foreign original drugs.