How much does a box of Ruxolitinib cost?

Ruxolitinib is a Janus kinase inhibitor (JAK inhibitor) that is selective for JAK1 and JAK2 subtypes. Ruxolitinib, an ingredient in Ruxolitinib tablets, inhibits JAK signaling dysregulation associated with myelofibrosis. JAK1 and JAK2 recruit signal transducers and activators of transcription (STATs) to cytokine receptors, resulting in the regulation of gene expression.

In the United States and the European Union, ruxolitinib tablets are indicated for the treatment of disease-related splenomegaly or symptoms in adults with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), postpolycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis. Ruxolitinib tablets are also indicated for the treatment of polycythemia vera in adults who are resistant or intolerant to hydroxyurea, for the treatment of steroid-refractory acute graft-versus-host disease in patients 12 years of age and older, and for the treatment of chronic graft-versus-host disease (cGVHD) after failure of one or two systemic therapies in patients 12 years of age and older.

Ruxolitinib tabletsThe original drug has been launched in China and is included in the scope of Class B medical insurance. It is limited to patients who meet the indications. Specification The price of each box of 5mg*60 tablets may be around RMB 3,000. The Turkish version of ruxolitinib tablets listed overseas, Specifications20mg*56 tablets, may be priced around RMB 8,000 per box (the price may fluctuate due to exchange rates). There are also ruxolitinib tablets produced in other countries. For example, the price of 5mg*50 tablets produced by Bangladesh Yaopin International may be around 1,400 yuan per box (the price may fluctuate due to exchange rates). Its pharmaceutical ingredients are basically the same as those of domestic and foreign original drugs.