Are Ruxolitinib tablets available in India?

It is understood that there are no original drugs or generic drugs for Ruxolitinib produced by Indian pharmaceutical companies. Ruxolitinib tablets are a prescription drug administered orally. It is a drug that targets proteins in cells and prevents their growth. It is used to treat myelofibrosis, polycythemia vera, and graft-versus-host disease. The common format is oral tablets, which can be taken orally with a glass of water as directed.

Ruxolitinib inhibits cytokine-induced STAT3 phosphorylation in whole blood from patients with myelofibrosis and polycythemia vera. In patients with myelofibrosis and polycythemia vera, STAT3 phosphorylation reaches maximal inhibition at 2 hours after administration of ruxolitinib tablets and returns to near baseline after 10 hours. The JAK-STAT signaling pathway plays a role in regulating the development, proliferation, and activation of several immune cell types important in the pathogenesis of graft-versus-host disease.

Ruxolitinib tabletsThe original drug has been launched in China and is included in the scope of Class B medical insurance. It is limited to patients who meet the indications. Specification The price of each box of 5mg*60 tablets may be around RMB 3,000. The Turkish version of ruxolitinib tablets listed overseas, Specifications20mg*56 tablets, may be priced around RMB 8,000 per box (the price may fluctuate due to exchange rates). There are also ruxolitinib tablets produced in other countries. For example, the price of 5mg*50 tablets produced by Bangladesh Yaopin International may be around 1,400 yuan per box (the price may fluctuate due to exchange rates). Its pharmaceutical ingredients are basically the same as those of domestic and foreign original drugs.