How long does Riluzole extend life?

Riluzole (Riluzole) is the first therapy approved in the United States to treat amyotrophic lateral sclerosis (ALS) and is available as a tablet called Rilutek. It is also currently the main ingredient in two other approved formulations: Exservan (riluzole oral film) and Tiglutik (riluzole oral suspension). The exact mechanism by which riluzole treats ALS is unknown, but the drug is thought to help slow the degeneration of nerve cells by blocking the release of the chemical messenger glutamate.

Research consistently shows that riluzole can slow the progression of ALS symptoms and improve survival rates, but some uncertainty remains about the optimal timing of treatment. 72.1% received riluzole, and the overall median survival time of patients receiving riluzole was significantly higher (22.6 vs. 20.2 months). Statistical analysis showed that treatment with riluzole reduced the risk of death by more than 20%. The researchers estimated that a one-year delay in starting riluzole might decrease median survival by 1.9 months, and a two-year delay might decrease median survival by 4.9 months.

The original drug Riluzole has been launched in China and has entered the scope of Class B medical insurance. Specifications The price of 50mg*56 tablets per box may be around 4,000 RMB. The price of the Turkish version of Riluzole’s original drug, 50mg*56 tablets, sold overseas may be around RMB 1,200 per box (the price may fluctuate due to exchange rates). There are also generic drugs produced in other countries. The price of a box of 50mg*30 tablets produced by an Indian pharmaceutical factory may be around RMB 1,300 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs. For specific prices and drug information, please consult Yaode Medical Consultants.