What are the side effects of Elobixibat?

Elobixibat (Elobixibat) is a drug used to treat chronic constipation and is a bile acid transporter inhibitor. Although it is effective in relieving constipation symptoms, like all medications, eloxibate may cause some side effects. Here are some details about the possible side effects of eloxibate:

1.Abdominal pain and bloating: This is one of the most common side effects when using eloxibat. Patients may experience mild to moderate abdominal pain, stomach discomfort, or a feeling of bloating.

2.Diarrhea: Diarrhea is another common side effect of eloxibate. It may occur early in treatment but may lessen over time. Diarrhea may cause more frequent bowel movements and loose stools.

3.Nausea and vomiting: Some people may experience mild nausea or vomiting while taking eloxibat.

4.Gastrointestinal discomfort: including upper abdominal discomfort, heartburn, etc.

5.Headache: Some people may experience mild headaches while taking eloxibat.

6.Back pain: Individual patients may report back pain or discomfort.

7.Gallstones: The mechanism of action of eloxibat is related to the bile acid cycle, so it may affect the metabolism of bile acids. Patients taking high doses of eloxibat for a long time may be at increased risk of gallstones.

8.Electrolyte imbalance: Prolonged diarrhea may lead to an imbalance of electrolytes such as sodium, potassium, magnesium, etc., so the levels of these electrolytes need to be monitored regularly during the use of eloxibat.

9.Fecal incontinence: In some cases, eloxibate may cause fecal incontinence or uncontrollable bowel movements.

10.Drug Interactions: Eloxibate may interact with other drugs, especially drugs that affect bile acid metabolism. Therefore, your doctor should be informed of all medications you are taking while taking eloxibat.

11.Allergic reactions: Although rare, some individuals may have allergic reactions to eloxibate, including skin itching, rashes, urticaria, etc.

12.Discomfort: Some patients may report some mild discomfort after using eloxibat, such as dry mouth, oral discomfort, etc.

Overall, eloxibat is generally considered a relatively safe drug, but different individuals may respond differently to the drug. If serious or persistent side effects occur while taking eloxibat, patients should stop taking the medication immediately and consult a doctor. For those patients who are concerned about side effects, it would be wise to have a full discussion with their doctor and understand the potential risks and benefits. Proper use of medications under the guidance of a doctor can minimize possible side effects.

Eloxibat is not currently on the market in China, so patients cannot purchase it domestically and need to purchase eloxibat through overseas channels. There are only original eloxibate drugs available abroad, mainly from Japan, and the price is around 2,200yuan.