Is there any difference between Enasidenib from Ziskar Pharmaceuticals in Bangladesh and Nanta Pharmaceuticals from Laos? Is there a big difference in efficacy?

It is understood that there are currently no generic Ensidipine (Enasidenib) sold by Laos Nanta Pharmaceuticals. The common Ensidipine generics are Bangladesh Zisika Pharmaceuticals. The drug ingredients are basically the same as those of the Ensidipine generic drugs. However, the manufacturers and specifications are different, and the prices are different.

EnsidipineThe original drug was originally developed byAgios Pharmaceuticals developed and subsequently approved for marketing, Trade nameIdhifa, is a drug used to treat isocitrate dehydrogenase A drug for relapsed or refractory acute myeloid leukemia (AML) in people with specific mutations in the 2(IDH2) gene. Patients treated with this drug need to be determined by an FDA-approved IDH2 companion diagnostic test. Enasidenib, the active ingredient in ensidipine, is a small molecule inhibitor of isocitrate dehydrogenase 2 (IDH2) enzyme. In vitro, ensidipine targets mutant IDH2 variants R140Q, R172S, and R172K at approximately 40-fold lower concentrations than the wild-type enzyme.

Ensiidi plain investigational medicine is not currently on the market in the country, nor is it covered by medical insurance. The price of ensidipi plain research medicine when it is launched overseas is very high. Its price is around RMB 30,000 (the price may fluctuate due to the exchange rate). The expensive price may increase the pressure on families with heavy financial burdens. Ensidipine generic drug from Bangladesh Ziskar Pharmaceuticals, Specifications50mg* The price of 60 tablets per box may be around RMB 4,900 (the price may fluctuate due to exchange rate effects). The price is relatively cheap. For specific prices and drug information, please consult Yaode Medical Consultant.