How long does it take for Rituximab to be effective in treating arthritis?

Rituximab (Rituximab) has been shown to be an effective treatment for rheumatoid arthritis in three randomized controlled trials and is now approved for refractory rheumatoid disease. In the United States, the FDA has approved it for use in combination with methotrexate (MTX) to reduce the signs and symptoms of moderately to severely active rheumatoid arthritis (RA) in adult patients who have had an inadequate response to one or more anti-TNF-alpha therapies. In the EU, the license is slightly more restrictive, and it is licensed in combination with MTX for patients with severe active RA who have had an inadequate response to one or more anti-TNF therapies. The most dangerous but rarest side effect is progressive multifocal leukoencephalopathy (PML) infection, which is often fatal; however, only rare cases have been documented in autoimmune diseases.

Rituximab has been launched in China and has entered the scope of Class B medical insurance. The use of rituximab must be carried out by doctors and medical staff. It is a strictly controlled drug and its purchase and use may be restricted. SpecificationsThe price of each box of 500mg/500mL may be around RMB 8,000, which is relatively expensive. Rituximab has also been launched overseas. The price of the original Indian version of 500mg/500mL per box may be around RMB 3,000 (the price may fluctuate due to exchange rates) . There are also generic rituximab drugs produced by other pharmaceutical companies in India. The price of 500mg/500mL per box may be around 1,500 yuan (the price may fluctuate due to exchange rates). Its drug ingredients are basically the same as those of domestic and foreign original drugs.