How much does Pirfenidone cost?

Pirfenidone (Pirfenidone) is a synthetic pyridone drug that is an anti-fibrotic drug with anti-inflammatory and antioxidant properties and can be used to treat idiopathic pulmonary fibrosis (IPF). Idiopathic pulmonary fibrosis is a chronic progressive interstitial pneumonia. Although its mechanism of action is not fully understood, pirfenidone is mainly used to modulate the tumor necrosis factor (TNF) pathway and regulate cellular oxidation.

Fibrosis is the formation of scar tissue as part of the body's natural repair process after tissue damage. Idiopathic pulmonary fibrosis involves chronic inflammation and the progressive formation of fibrous tissue in the walls of the air-containing chambers of the lungs. Because the injury that causes these changes is unknown, it is called idiopathic injury. Pirfenidone reduces the production of transforming growth factor-β1 (TGF-β1), a key profibrotic and proinflammatory cytokine associated with idiopathic pulmonary fibrosis. By inhibiting TGF-β1, pirfenidone inhibited TGF-β1-induced differentiation of human lung fibroblasts into myofibroblasts, thereby preventing excessive collagen synthesis and extracellular matrix production.

Pirfenidone has been approved for marketing in China under the trade name of Asri. It has entered the scope of Class B medical insurance and is limited to patients with idiopathic pulmonary fibrosis. The specifications produced by domestic pharmaceutical factoriesThe price of 100mg*54 capsules per box is around RMB 500. There are also generic pirfenidone drugs produced in other countries overseas. For example, the price of a box of 200mg*30 tablets produced by an Indian pharmaceutical factory is around RMB 100 (the price may fluctuate due to the exchange rate). The ingredients of the generic drugs are basically the same as those of the original drug. For more drug information and specific prices, please consult Yaode Medical Consultant.