Chinese instructions for Edaravone

1. Indications: Edaravone (Edaravone) is an antioxidant commonly used to treat patients with spinal muscular atrophy (ALS). ALSis a progressive degenerative disease of the nervous system, and edaravone is used to slow its progression.

2. Mechanism of action: Edaravone, as an antioxidant, can reduce cellular oxidative stress by scavenging free radicals, thereby protecting nerve cells from oxidative damage. This mechanism of action may help slow the progression of ALS.

3. Pharmacology: Edaravone may help protect nerve cells from damage by reducing oxidative stress and inflammatory response. It may also play a role in cell signaling pathways, but the specific mechanisms still require further study.

4. Dosage and usage: The recommended usage of edaravone is intravenous injection once a day, usually 30 minutes. Dosage and duration of treatment may vary depending on individual circumstances and should be used under the supervision of a physician.

5. Side effects: Edaravone may cause some side effects, including but not limited to headache, dizziness, nausea, vomiting, skin allergies, etc. If serious adverse reactions occur, you should stop using the drug immediately and consult your doctor.

6. Warnings and precautions:

1.During the use of edaravone, liver function, renal function and blood routine should be monitored regularly.

2.Pregnant women, lactating women and women planning pregnancy should consult a doctor before use.

3.During use, if serious adverse reactions such as difficulty breathing or severe headache occur, you should seek medical attention immediately.

7. Contraindications: Edaravone may not be suitable in certain circumstances, such as patients who are allergic to drug ingredients, or under specific medical conditions. Use should be decided under the guidance of a doctor.

8. Drug interactions: Edaravone may interact with other drugs, especially other drugs currently being used. Before using edaravone, you should tell your doctor about all the medicines you are taking, including prescription drugs, over-the-counter drugs, and supplements.

9. Medication for special groups: For special groups such as elderly patients and children, the dosage or monitoring frequency may need to be adjusted. Should be used under the advice of a doctor.

10. Listing and price situation: Edaravone has been launched in China and has been included in medical insurance. Patients can purchase it domestically, and the domestic price is relatively cheap. Please consult the local hospital pharmacy or medical insurance bureau for specific prices and reimbursement policies.