What are the side effects of Enfortumab?

Enfortumab vedotin-ejfv is a drug used to treat advanced or refractory urothelial carcinoma (urothelial carcinoma). It targets the Nectin-4 protein on the surface of urothelial cancer cells and delivers toxins into the cancer cells, thereby inhibiting their growth and spread. However, drug treatment is often accompanied by a range of side effects, which may vary depending on individual differences, medication dosage, the patient's health status, and other factors. The following are possible side effects of ennozumab, but please note that this is general information only. Please consult your doctor or professional medical resource for the most accurate and up-to-date information for your specific situation.

1.Digestive system side effects:

Nausea: Medication may cause nausea and affect appetite and eating habits.

Vomiting: Some patients may experience vomiting, leading to loss of physical strength and dehydration.

Diarrhea: Medications may affect the intestines, causing diarrhea or abdominal discomfort.

2.Skin reaction:

Skin rash: Some patients may develop rash, erythema, itching and other skin problems.

Dryness: Skin may become dry and require additional skin care.

3.Fatigue:

Medication often causes fatigue, both physical and psychological.

4.Anemia:

Ennozumab may affect hematopoiesis, causing anemia (decreased hemoglobin levels).

5.Nervous system response:

Headache: Some patients may experience headaches, which may vary in severity.

Insomnia: Medication may have an impact on sleep, causing insomnia problems.

Difficulty concentrating: Some patients may experience difficulty concentrating or cognitive decline.

6.Abnormal liver and kidney function:

Drugs may have an impact on liver and kidney function, and liver and kidney indicators need to be monitored to ensure that drug handling does not cause further problems.

7.Cardiovascular problems:

Some drugs may affect the cardiovascular system and cause heart problems.

8.Immune system response:

Ennosumab may affect the immune system, causing an excessive immune response or immunosuppression.这可能会导致感染的风险增加，需要密切监测。

9.Eye problems:

Drugs may cause eye problems, such as eye pain and blurred vision.

It is important to emphasize that the severity of side effects varies from individual to individual. If you or someone you know is being treated with ennosumab, it is important to follow your doctor's recommendations, get regular checkups, and contact a medical professional immediately if you experience any discomfort or unusual reactions. Only a medical professional can provide you with the correct guidance and advice based on your specific situation.

Ennosumab is not currently available in China, so patients cannot purchase it domestically and need to purchase ennosumab through overseas channels. There are only enromonumab original drugs in foreign countries, and there are no generic drugs. They are mainly Japanese original drugs, and the price is more than 10,000 yuan.