Chinese instructions for Febuxostat

1. Indications: Febuxostat is used to treat hyperuricemia and is suitable for the treatment of gout and its complications. Hyperuricemia can lead to the deposition of uric acid crystals, leading to arthritis, stone formation, etc.

2. Mechanism of action: Febuxostat is a selective urate oxidase inhibitor that can prevent the activity of key enzymes that produce uric acid in the body. By reducing the production of uric acid, it helps reduce the concentration of uric acid in the body, thereby reducing the deposition of uric acid crystals.

3. Pharmacology: Febuxostat inhibits the activity of urate oxidase by binding to urate oxidase, thereby reducing the production of uric acid. It helps reduce inflammation and damage caused by hyperuricemia by regulating the balance of uric acid metabolism in the body.

4. Dosage and usage: It is generally recommended that adults take febuxostat orally. The starting dose is 40 mg / days. The dose can be gradually adjusted under the guidance of a doctor. The maximum dose is generally 120 mg/day. The drug should be taken with food to reduce gastrointestinal discomfort.

5. Side effects: Common side effects include nausea, vomiting, headache, rash, etc. A small number of patients may experience severe allergic reactions, liver function abnormalities, etc. If any adverse reactions occur, you should consult your doctor promptly.

6. Warnings and precautions:

1.Monitor liver function and blood uric acid levels regularly during use.

2.Avoid drinking alcohol as it may affect the effectiveness of medicines.

3.Be aware that the drug may interact with other drugs. Be sure to inform your doctor about other drugs you are using.

7. Contraindications:

1.Patients allergic to febuxostat.

2.Patients with severe liver dysfunction.

8. Drug interactions: Febuxostat may interact with certain drugs, especially with certain anticoagulant drugs, anti-epileptic drugs, etc. Before using febuxostat, be sure to tell your doctor about any other medications you are taking.

9. Medication for special groups:

1.Pregnant women, lactating women and children should use it under the guidance of a doctor.

2.Elderly patients generally do not need special dosage adjustments, but they still require physician supervision.

10. Listing and price situation: Febuxostat has been launched in China and has been included in medical insurance. Patients can purchase it domestically.