Fulvestrant dosage and usage

Fulvestrant (Fulvestrant) is a drug used to treat estrogen receptor-positive (ER+) breast cancer. Its dosage and usage are adjusted based on clinical conditions and physician guidance. The dosage and usage of fulvestrant will be introduced in detail below.

1. Dosage and administration: Fulvestrant is usually administered by intramuscular injection, which can ensure the slow release of the drug and maintain a stable level of the drug in the body. The dosage and frequency of fulvestrant may vary during the initial and maintenance phases of treatment.

1.1 Initial treatment phase: Usually, in the initial treatment phase, the recommended dosage of fulvestrant is 500 mg (mg), once every two weeks for three consecutive times. This means patients will receive three intramuscular injections of 500 mg each over the first six weeks. Initial treatment is designed to establish the initial concentration of the drug in the body so that efficacy is achieved quickly when treatment is initiated.

1.2 Maintenance treatment phase: The dosage during the maintenance treatment phase will change. After initial treatment, the recommended dose of fulvestrant is 500 mg per injection every four weeks. The goal of this phase is to maintain stable levels of the drug in the body to continue inhibiting estrogen receptor activity.

2. Doctor’s guidance: The dosage and usage of fulvestrant need to be adjusted and guided by a doctor according to the patient’s specific conditions. Doctors will consider several factors, including the patient's age, overall health, other medications they are taking, and the severity of their condition. Based on these factors, your doctor may decide if the dose of the drug needs to be adjusted or if monitoring is needed in specific situations.

3. Follow medical advice: When using fulvestrant, patients should strictly follow the doctor's instructions and recommendations. Here are some things to note:

3.1 Take medicine on time: Patients should receive their medication injections exactly on time, as recommended by their doctor. Stable plasma concentrations of the drug are critical to therapeutic efficacy, so it is important to follow the correct dosing schedule.

3.2 Avoid missing medications: Try to avoid missing medications. If for any reason you miss your injection, you should contact your doctor as soon as possible for further guidance.

3.3 Consult your doctor: During the use of fulvestrant, if the patient has any concerns, discomfort or side effects, he should consult his doctor immediately. Doctors can decide whether adjustments or other interventions are needed based on the patient's symptoms and experience.

3.4 With other treatments: Sometimes, fulvestrant may be used with other drugs, such asCDK4/6 inhibitors. In this case, patients need to make sure to follow the usage and dosage instructions for all medications at the same time.

Fulvestrant is a drug for the treatment of estrogen receptor-positive breast cancer. Its dosage and usage are adjusted according to the doctor's guidance and the patient's specific conditions. Accurately following the doctor's advice and receiving medication injections on time are important steps to ensure the effectiveness and safety of treatment. During the medication process, patients should maintain communication with their doctors and promptly report any discomfort or problems in order to obtain timely guidance and intervention.

Fulvestrant injection has been launched in China and has been included in medical insurance. Patients can buy it domestically. The price of domestically imported original drugs is around 5,000 to 6,000 yuan, while domestic drugs are slightly cheaper. For specific prices, please consult the local hospital pharmacy or the medical insurance bureau. There is only Fulvestrant's original drug abroad. The cheaper original drugs are mainly the Turkish original drug and the Indian version of the original drug. The price is around 1,000~2,000 yuan, and the ingredients and efficacy of the original drugs at home and abroad are the same.