How much does a box of vepotuzumab (POLIVY) cost?

Vepotolizumab (POLIVY) is used with bendamustine and rituximab in adults to treat certain types of non-Hodgkin lymphoma (NHL, a cancer that starts in a type of white blood cell that usually fights infections) that do not improve or improve, such as positive diffuse large B-cell lymphoma (DLBCL) but come back after treatment with at least two other chemotherapy drugs. Vepotuzumabbelongs to a class of drugs called antibody-drug conjugates, which work by killing cancer cells.

Vepotolizumab is a powder that is mixed with liquid and given intravenously (into a vein) by a doctor or nurse, usually 30 to 90 minutes on the first day of a 21-day cycle. Depending on your doctor's recommendation, this cycle can be repeated 6 times or more, and the length of treatment depends on the body's response to the medication and the side effects experienced. Your doctor may need to delay treatment, adjust the dose, or stop treatment if certain side effects occur, such asperipheral neuropathy, nausea, fatigue, diarrhea, constipation, hair loss, and mucositis.

Vepotolizumab's patent medicine has been launched in China. Due to its short time on the market, it has not yet entered the scope of medical insurance. It is an injectable preparation. The price of 30 mg per box may be around RMB 10,000. The price of the Hong Kong version of 140 mg per box may be around RMB 60,000 (the price may fluctuate due to exchange rates) overseas. The price of the European version of vepotuzumab on the market, Specifications140 mg per box, may be around 90,000 yuan (the price may fluctuate due to the exchange rate). The ingredients of domestic original drugs are basically the same as those of foreign original drugs, and they are expensive. There are currently no generic versions of vepotuzumab on the market.