How many vials of vepotuzumab (POLIVY) are needed for one treatment?

Vepotolizumab (POLIVY) is available by prescription only, and treatment must be under the supervision and guidance of a healthcare professional experienced in diagnosing and treating cancer, Vepotuzumab is administered as a 90-minute intravenous infusion along with rituximab and bendamustine in 21-day cycles. The dose is based on the patient's weight and lasts for 6 cycles. The recommended dose is 1.8 mg/kg.

Before receiving vepotuzumab, patients are given acetaminophen and an antihistamine to reduce the risk of a reaction to the infusion. If the patient experiences an infusion-related reaction, the infusion should be slowed or interrupted. Doctors may reduce or stop the dose of vepotuzumab if a person develops side effects that affect blood cells. The common domestic formulation of vepotuzumab is 30mg. If a patient weighs 50kg is calculated, a treatment with vepotuzumab may require about 3 pills. For specifics, the attending doctor needs to be consulted for judgment.

Vepotolizumab's patent medicine has been launched in China. Due to its short time on the market, it has not yet entered the scope of medical insurance. It is an injectable preparation. The price of 30 mg per box may be around RMB 10,000. The price of the Hong Kong version of 140 mg per box may be around RMB 60,000 (the price may fluctuate due to exchange rates) overseas. The price of the European version of vepotuzumab on the market, Specifications140 mg per box, may be around 90,000 yuan (the price may fluctuate due to the exchange rate). The ingredients of domestic original drugs are basically the same as those of foreign original drugs, and they are expensive. There are currently no generic versions of vepotuzumab on the market.