How many versions of Gilteritinib are there?

Gilteritinib (Gilteritinib) is a drug that belongs to a class of drugs called "targeted therapies." Giritinib is mainly used to treat acute myeloid leukemia (Acute Myeloid Leukemia, AML) patients with FLT3 gene mutation subtypes. FLT3 is a receptor tyrosine kinase whose mutations are relatively common in AML patients. These mutations cause leukemia cells to proliferate abnormally, making them important targets for treatment.

Giritinib has both original and generic versions. Currently, the original version of giritinib has been launched in China, but it is not covered by medical insurance. If patients need it, they can go to the hospital to buy it at their own expense, but the price is very high, about 35,000 yuan. Please consult the local hospital pharmacy for specific prices.

Foreign original drugs of gilitinib are even more expensive. For example, the price of the Hong Kong version of the original drug is around 90,000 yuan, and the European version of the original drug is as high as more than 200,000 yuan, which is simply unaffordable for ordinary patients.

There are already foreign generic drugs of Giritinib on the market, mainly Laos generic drugs. The price is about four to five thousand yuan, which is relatively cheap. In terms of drug ingredients, the ingredients of domestic and foreign original gilitinib drugs are basically the same as those of generic drugs.

Giritinib prevents the growth and differentiation of leukemia cells by inhibiting the activity of FLT3 receptor tyrosine kinase. It has been clinically tested in AML patients and demonstrated significant efficacy against certain FLT3 gene-mutated AML subtypes.

It needs to be emphasized that giritinib is a therapeutic drug that specifically targets FLT3 mutations and does not have the same effect on other types of leukemia or tumors. Patients should use gilitinib under the supervision of a doctor and follow the advice of their medical professional to determine whether this drug is appropriate and how to use it correctly.