Pembrolizumab effects and side effects

Pembrolizumab is an immune checkpoint inhibitor that enhances the immune system's ability to attack tumors by blocking the PD-1 (programmed death-1) signaling pathway. By inhibiting the interaction between PD-1 and PD-L1, it enhances the body's immune system's ability to attack cancer cells, thereby inhibiting the growth and spread of cancer. It is widely used in the treatment of different types of malignant tumors, such as melanoma, non-small cell lung cancer, renal cancer, head and neck squamous cell carcinoma, etc.

Because pembrolizumab enhances the activity of the immune system, it may cause the immune system to attack normal tissues, causing immune-related side effects. These side effects include fatigue, fever, rash, diarrhea, nausea, vomiting, etc. Serious immune-related side effects may include pneumonia, hepatitis, thyroid dysfunction, nephritis, and neuritis. In addition to immune-related side effects, pembrolizumab may cause other side effects, such as headache, joint pain, myalgia, back pain, cough, and insomnia.

PembrolizumabThe original drug is already on the market in China. SpecificationsThe price per box of 100mg/4ml may be around RMB 15,000. This drug is a strictly controlled drug and has not yet been included in medical insurance. Pembrolizumab The price of the European version of the original drug 100mg/4ml per box may be around RMB 25,000, and the price of the Turkish version of 100mg/4ml per box may be around 10,000 RMB (the price may fluctuate due to the exchange rate). The ingredients of the original drugs at home and abroad are basically the same, and they are expensive. There are currently no generic versions of Pembrolizumab available overseas.