What to do if you are resistant to Pembrolizumab

Regardless of cancer type, there were no clinically meaningful exposure-response relationships in trials of pembrolizumab at doses of 200 mg or 2 mg/kg every 3 weeks. If resistance to pembrolizumab occurs, it is recommended to contact a doctor immediately for further evaluation and adjustment of the treatment plan. They can consider strategies based on the patient's specific situation.

The emergence of drug resistance may be related to the genetic mutations of tumor cells. Genetic testing is required to understand the characteristics and mutations of tumor cells in order to choose a more suitable treatment plan. The effectiveness of pembrolizumab may be increased when combined with other anticancer drugs or immunotherapy drugs. For example, combinations with chemotherapy drugs, targeted therapy drugs, or other immune checkpoint inhibitors can be tried. Clinical trials may also provide some new treatment options, especially for tumors that develop drug resistance.

PembrolizumabThe original drug is already on the market in China. SpecificationsThe price per box of 100mg/4ml may be around RMB 15,000. This drug is a strictly controlled drug and has not yet been included in medical insurance. Pembrolizumab The price of the European version of the original drug 100mg/4ml per box may be around RMB 25,000, and the price of the Turkish version of 100mg/4ml per box may be around 10,000 RMB (the price may fluctuate due to the exchange rate). The ingredients of the original drugs at home and abroad are basically the same, and they are expensive. There are currently no generic versions of Pembrolizumab available overseas.