What is Gemtuzumab/Gemtuzumab (MYLOTARG)?

Gemtuzumab/Gemtuzumab (MYLOTARG) is a drug commonly used to treat acute myeloid leukemia ( AML), especially CD33 positive AML patients. Here is some basic information about gemtuzumab/gemtuzumab:

1.Type of drug:Gemtuzumab/Gemtuzumab is a monoclonal antibody drug. Monoclonal antibodies are antibodies that target a specific protein (in this case CD33) and can be used to treat specific types of cancer.

2.Mechanism of action:Gemtuzumab/The mechanism of action of gemtuzumab involves binding to the CD33 antigen on the surface of AML cells. Once gemtuzumab/gemtuzumab binds to CD33 antigen, it can activate the host immune system, such as natural killer cells ( span>NK cells) and macrophages, guiding them to attack and killCD33positiveAML cells. This mechanism of action helps reduce the number of leukemia cells.

3.Indications:Gemtuzumab/Gemtuzumab is usually used to treat AML patients, especially for newly treated AMLCD33positiveAML, as well as relapsedAMLpatients or AMLpatients who cannot tolerate traditional treatment.

4.Usage and dosage:Gemtuzumab/GemtuzumabUsually administered via intravenous injection. The specific dosage and treatment plan will be determined according to the patient's specific condition and the doctor's recommendations.

5.Side effects: Using gemtuzumab/gemtuzumab may cause some side effects, including fever, headache, nausea, vomiting and effects on the immune system. Therefore, when receiving gemtuzumab/gemtuzumab treatment, patients need to be under the supervision of a doctor and undergo relevant examinations regularly to monitor the effect of the treatment and the patient's safety.

Gemtuzumab/GemtuzumabIt is not currently on the market in China, so it cannot be included in medical insurance. Patients cannot purchase it domestically and need to purchase it through overseas channelsGemtuzumab/Gemtuzumab. Foreign Gemtuzumab/Gemtuzumab is only Pfizer’s original drug, which is expensive, and the cheaper ones are mainly Turkish original drugs. The price of the drug is around 45,000 yuan, and the price of the original drug in Hong Kong, China is around 65,000 yuan, and the ingredients and efficacy of the original drug are consistent.