How long does it take for Pralsetinib to take effect?

Pralsetinib (Pralsetinib) is a drug used to treat certain types of cancer, especially thyroid or lung cancers that carry mutations in the ret gene. Depending on individual circumstances, the time it takes for Platinib to be effective may vary. If a patient develops certain side effects while using it, the doctor may reduce its dose or stop treatment temporarily or permanently.

The recommended dose of platinib is 400 mg once daily, with treatment continued until disease progression or unacceptable toxicity. Platinib has been shown to be 57% and 70% effective in patients who had previously received platinum-based chemotherapy and in treatment-naïve patients, respectively. Generally speaking, Platinib can begin to show some benefit within a few weeks of starting treatment. However, the specific effectiveness and duration of treatment may depend on factors such as the type and stage of the cancer, severity of the disease, and individual physiological differences. For patients requiring elective surgery, discontinue platinib for at least 5 days before surgery and do not give it for at least 2 weeks after major surgery until the wound has completely healed.

It is understood that the original drug Platinib has been launched in China, but it has not yet entered the scope of medical insurance. The price of each box of 100mg*120 tablets may be around 60,000 yuan, which is expensive. The price of the European version of 100mg*60 capsules sold overseas may be around 40,000 yuan per box, and the price of the American version may be around 150,000 yuan per box (prices may fluctuate due to exchange rates). The ingredients of domestic and foreign original drugs are basically the same. There is currently no generic version of Platinib available on the market. Please consult your medical consultant for specific prices and drug details.