I took Pralsetinib for more than ten days without any effect.

If the patient takes Pralsetinib (Pralsetinib) for more than ten days and has no effect, it is recommended to communicate with your attending doctor in time to understand your symptoms and treatment response. The patient may be advised to undergo some examinations to determine whether there are other problems or to adjust the medication plan. Treatment with platinib is usually continued until unacceptable toxicity occurs and treatment is discontinued.

Treatment with platinib produced robust efficacy and was well tolerated in treatment-naïve patients with advanced RET fusion-positive non-small cell lung cancer. In cultured cells and cells containing oncogenic RET fusions or mutations (including KIF5B-RET, CCDC6-RET, RET M918T, RET C634W, RET V804E, RET V804L, and RET V804M) showed anti-tumor activity in animal tumor implantation models. praxitinib prolonged the survival of mice with intracranial implantation of tumors expressing KIF5B-RET or CCDC6-RET.

It is understood that the original drug Platinib has been launched in China, but it has not yet entered the scope of medical insurance. The price of each box of 100mg*120 tablets may be around 60,000 yuan, which is expensive. The price of the European version of 100mg*60 capsules sold overseas may be around 40,000 yuan per box, and the price of the American version may be around 150,000 yuan per box (prices may fluctuate due to exchange rates). The ingredients of domestic and foreign original drugs are basically the same. There is currently no generic version of Platinib available on the market. Please consult your medical consultant for specific prices and drug details.