What drugs should be taken with lxazomib?

Ixazomib is often used as part of a treatment regimen for multiple myeloma (Multiple Myeloma), in combination with other drugs to increase the effectiveness of the treatment. This combination treatment regimen can be formulated according to the patient's specific situation and disease stage. The following are some common ixazomib combination regimens:

1.Lenalidomide (Lenalidomide): The combination of ixazomib and lenalidomide is a common treatment option, especially for maintenance treatment of multiple myeloma. The two drugs work synergistically to prolong progression-free survival (Progression-Free Survival, PFS) and improve survival rates.

2.Dexamethasone (Dexamethasone): Dexamethasone is a hormonal drug that is often used together with ixazomib and lenalidomide to further enhance the therapeutic effect. It helps reduce inflammation and symptoms associated with the disease, while also reducing the growth of cancer cells.

3.Implantable drugs: Sometimes, implantable drugs such as bortezomib (Bortezomib) or carfalimus (Carfilzomib) can also be used in combination with ixazomib, especially for patients whose disease progresses quickly or is difficult to control. These drugs also belong to the proteasome inhibitor class and have a similar mechanism of action to ixazomib.

4.Immunomodulators: Sometimes, immunomodulators such as tazib (Thalidomide) or palidupil (Pomalidomide) can also be used in combination with ixazomib to enhance the function of the immune system and inhibit the growth of cancer cells.

5.Other drugs: In addition to the above drugs, combination drug regimens for the treatment of multiple myeloma may also include other drugs, depending on the patient's disease characteristics, treatment goals, and physician recommendations.

The original drug of Ixazomib has been launched in China and has been included in medical insurance. Patients can purchase it domestically, but the price is still relatively high. The price is about 15,000 to 6,000 yuan. For specific prices and medical insurance reimbursement policies, please consult the local hospital pharmacy or medical insurance bureau. Foreign original drugs are even more expensive. The cheaper foreign ones are ixazomib generics, mainly Laotian generics. The price is more than 1,000 yuan, and the ingredients of the original drugs and generic drugs are basically the same.