The role of lxazomib

Ixazomib (Ixazomib) is a proteasome inhibitor whose main function is to inhibit the function of the proteasome. The proteasome is an organelle within cells responsible for breaking down and degrading proteins, which is one of the key processes in cells to maintain normal functions. The mechanism of action of ixazomib involves the following aspects:

1.Proteasome inhibition: Ixazomib exerts its effects by interfering with the normal function of the proteasome. The proteasome contains proteases that are responsible for breaking down waste proteins and regulating protein degradation within the cell. By inhibiting the function of the proteasome, ixazomib interferes with the normal degradation process of proteins, causing abnormal proteins to accumulate in cells, thereby affecting the growth and reproduction of multiple myeloma cells.

2.Anti-cancer effect: Multiple myeloma is a blood cancer that mainly occurs in plasma cells in the bone marrow. Ixazomib helps control the development of multiple myeloma by inhibiting the growth and reproduction of cancer cells and reducing the production of abnormal proteins. This can alleviate symptoms, reduce the risk of disease progression, and extend patient survival.

3.Treatment of multiple myeloma: Ixazomib is usually used for the treatment of multiple myeloma, including initial treatment, maintenance treatment and treatment of relapsed/refractory disease. It is often used with other drugs to form a combination treatment regimen to increase the effectiveness of the treatment.

The original drug of Ixazomib has been launched in China and has been included in medical insurance. Patients can purchase it domestically, but the price is still relatively high. The price is about 15,000 to 6,000 yuan. For specific prices and medical insurance reimbursement policies, please consult the local hospital pharmacy or medical insurance bureau. Foreign original drugs are even more expensive. The cheaper foreign ones are ixazomib generics, mainly Laotian generics. The price is more than 1,000 yuan, and the ingredients of the original drugs and generic drugs are basically the same.