How much does a box of Pazopanib cost?

Pazopanib is an oral multi-target tyrosine kinase inhibitor (TKI) that binds to vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) and several other key proteins responsible for angiogenesis, tumor growth and cell survival.

Pazopanib demonstrated activity against tumor growth in vivo and in vitro and was well tolerated in early clinical trials, with major side effects being hypertension, fatigue, and gastrointestinal disturbances. Pazopanib has shown clinical activity in several tumors, including renal cell carcinoma (RCC), breast cancer, soft tissue sarcoma, thyroid cancer, hepatocellular carcinoma, and cervical cancer. A phase III clinical trial in patients with metastatic renal cell carcinoma showed a significant improvement in progression-free survival, leading to its approval in the United States. In Metastatic Breast CancerThe combination of pazopanib and lapatinib is more effective than either alone.

PazopanibThe original drug has been launched in China and has entered the scope of Class B medical insurance, but reimbursement is limited to patients who meet the indications. The price of each box may be around 3,000 yuan. The price of pazopanib original drug specifications200mg*30 tablets marketed overseas may be around 1,000 RMB per box (the price may fluctuate due to exchange rates). There are also pazopanib generic drugs produced in other countries. The price of 200mg*30 tablets produced by Bangladesh pharmaceutical factory may be around 500 yuan per box (the price may fluctuate due to the exchange rate), which is cheaper. The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs.