How does Isotretinoin treat acne?

IsotretinoinAAcid (Isotretinoin), also known as retinoic acid (13-cis-retinoic acid), is a drug for treating acne. Its treatment principles involve many aspects, including reducing sebum secretion, promoting exfoliation of cuticles, reducing inflammation and inhibiting the growth of bacteria caused by acne. The following are the main principles of isotretinoinAacid in treating acne:

1.Reduce sebum secretion: The occurrence of acne is related to excess sebum secretion. This oil can cause blockage of hair follicles and form acne. IsotretinoinAacid reduces the skin's oil production by inhibiting the activity of sebaceous glands. This helps reduce the risk of clogged hair follicles and lessens the severity of acne.

2.Promote exfoliation of cuticles: The stratum corneum is a layer of cells on the surface of the skin, and they may block the entrance of the hair follicles. IsotretinoinAacid can cause keratinocytes to shed faster, reducing the possibility of hair follicle blockage. This helps prevent blackheads and whiteheads from forming.

3.Reduce inflammation: Acne is often accompanied by redness, swelling and inflammation of the skin. IsotretinoinAacid helps reduce these inflammatory reactions, making the skin look less red and swollen, reducing pain and discomfort.

4.Inhibit bacterial growth: IsotretinoinAacid may also have a certain antibacterial effect and can inhibit the growth of acne-causing bacteria (mainly Propionibacterium), thus reducing the risk of acne infection and exacerbation.

In short, the therapeutic mechanism of isotretinoinAacid mainly involves reducing sebum secretion, promoting exfoliation of cuticles, reducing inflammation, and inhibiting bacterial growth. The combined effect of these factors can help reduce the symptoms of acne and improve skin condition. However, it needs to be emphasized that isotretinoin is a very powerful drug that comes with a series of serious side effects and potential risks, so it can only be used under the supervision of a professional doctor. Patients must strictly follow the doctor's recommendations and receive regular monitoring and guidance from the doctor. In addition, women must use highly effective contraceptive measures while using isotretinoin to prevent pregnancy and reduce risks to the fetus.