Is there an Indian generic version of Ogaituzumab/Ointuzumab (Besponsa)?

Olintuzumab/Olintuzumab (Besponsa) is a drug used to treat acute lymphoblastic leukemia (Acute Lymphoblastic Leukemia, ALL). ALLis a malignant type of leukemia that usually affects lymphocytes, which are part of the body's immune system. Olintuzumab/Olintuzumabis a targeted drug with a specific mechanism of action and therapeutic target.

Olintuzumab/Olintuzumab currently does not have any generic drugs on the market, including Indian generics, only the original drug. Oxinutuzumab /Olintuzumab has been launched in China, but it is not included in medical insurance. The domestic price is around 60,000 to 70,000 yuan, which is very expensive. Patients can buy it domestically. There are only original drugs available abroad, mainly Pfizer’s original drugs, which cost more than 80,000 yuan.

Olintuzumab/Olintuzumab’s main mechanism of action is to interfere with the growth and survival of leukemia cells by targeting the CD22 antigen. CD22 is a protein located on the surface of B cells (a type of lymphocyte). In acute lymphoblastic leukemia, the leukemia cells often express CD22. Olintuzumab/Olintuzumab binds to the CD22 antigen and interferes with the normal functions of leukemia cells, including preventing cell proliferation and inducing apoptosis (cell death). Through these effects, oxinutuzumab/oxinutuzumab helps reduce the number of leukemia cells and improve the condition.

Olintuzumab/Olintuzumab is mainly used to treat adult B cell acute lymphoblastic leukemia (B-ALL). This type of leukemia usually affects adults, especially those who have become resistant to traditional treatments or have relapsed. Olintuzumab/OlintuzumabIt is usually administered by intravenous injection, and the usage and dosage will vary according to the specific situation of the patient. Treatment is usually divided into several cycles, each lasting several weeks, to achieve optimal results.